Disodium Cromoglycate as a Controller for Asthma

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Effect of disodium cromoglycate on exercise-induced asthma.

In eight patients with exercise-induced asthma, disodium cromoglycate was found to produce a definite inhibition of the post-exercise fall in forced expiratory volume in one second. This effect may be part of the cause for the subjective improvement experienced with this drug.

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Disodium cromoglycate in the prevention of induced asthma.

In 13 patients with allergic asthma disodium cromoglycate protected fully only two from an allergen-induced asthmatic attack.Inhalation of disodium cromoglycate did not improve lung function in five patients with long-standing chronic asthma.Previous clinical trials do not show convincing evidence that this drug improves bronchial asthma in a high percentage of cases, but it seems to help a sma...

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Inhaled disodium cromoglycate as maintenance therapy for childhood asthma: time to consign to history?

Disodium cromoglycate was introduced in the late 1960s as maintenance therapy for persistent asthma and as a modifier of exercise induced bronchoconstriction. It was the first treatment designed to manage the chronic nature of the disease and modify the inflammatory component without untoward systemic side eVects. After its antiinflammatory eVects had been established, clinical trial data began...

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Inhaled disodium cromoglycate (DSCG) as maintenance therapy in children with asthma: a systematic review.

BACKGROUND Disodium cromoglycate (DSCG) is included in the BTS guidelines on the treatment of asthma for use in children, but is now used only infrequently. We have identified and interpreted the findings of all published randomised, placebo controlled trials of DSCG in the prophylactic treatment of children with asthma. METHODS Several databases were searched to identify trials. Studies were...

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Actions of salbutamol, disodium cromoglycate, and placebo administered as aerosols in acute asthma.

The effects on the peak expiratory flow rate of the drug sequences, placebo-salbutamol-disodium cromoglycate and placebo-disodium cromoglycate-salbutamol administered via a nebuliser were examined in 35 children with asthma. Twenty children were each examined once within 4 hours of admission to hospital with an acute attack of asthma, and the remaining 15 children were examined later in the att...

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ژورنال

عنوان ژورنال: Internal Medicine

سال: 1996

ISSN: 0918-2918,1349-7235

DOI: 10.2169/internalmedicine.35.922